In this study, human lung cancer cells were cultured on 2D polystyrene plates and in 3D bioprinted gelatin methacrylate (GelMA) and Matrigel for 14 days to observe spheroid formation, cell morphology and junctional proteins. Bioprinting | Cancer research | BIO X

We introduce a miniaturized, highthroughput workflow in which single HEK293FT cells were sorted by the f.sight™ into 384-well PCR plates, then libraries were prepared with the I-DOT. I-DOT

A co-culture of human umbilical vein endothelial cells (HUVECs) and human dermal fibroblasts (HDFs) and a monoculture of induced pluripotent stem cells (iPSCs) were separately embedded in a selection of biomaterials for 7 days. Bioprinting | BIO X

Our study demonstrates that the c.bird™ improves mammalian cell growth in 96-well culture environments and closely imitates the shaker-flask culture in terms of cell growth profiles and protein yields. c.bird | Cell Line Development

In this study, a full thickness skin tissue model was bioprinted using the BIO X. The dermis was bioprinted using primary dermal fibroblasts embedded in GelXA SKIN bioink, and the epidermis, containing a high concentration of keratinocytes embedded in ColMA, was deposited on top of the dermis. Bioprinting | BIO X

In this application note, we explore the use of live-cell imaging to determine proliferation of label-free cells as well as fluorescently labeled cells. Cell imaging | CELLCYTE X

In this technical note, we explore cell proliferation using the CELLCYTE XTM live-cell imaging system to conduct time-course experiments. Cell imaging | CELLCYTE X

Bioprinting mini liver models for hepatotoxicity studies using a novel method of “droplet in droplet” encapsulation on the BIO X. BIO X | Drug screening

Assessing the effectiveness of the I-DOT, a low-volume noncontact liquid dispensing device, to form spheroids using the liquid overlay technique. Cancer research | I-DOT

Using the BIO X to evaluate drug efficacy in aggressive forms of breast and pancreatic cancer in 2D cell cultures vs. 3D bioprinted tumor models. Cancer research | BIO X

3D bioprinting a syngeneic tumor model of murine lung cancer on the BIO X to evaluate an immune checkpoint inhibitor (PD-1) in a 3D T cell cytotoxicity assay. Cancer research | BIO X