Application Notes

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Bioprinting mini liver models for hepatotoxicity studies using a novel method of “droplet in droplet” encapsulation on the BIO X. |

Evaluating Liver Toxicity in Bioprinted Mini Livers

| Bioprinting mini liver models for hepatotoxicity studies using a novel method of “droplet in droplet” encapsulation on the BIO X.
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Assessing the effectiveness of the I-DOT, a low-volume noncontact liquid dispensing device, to form spheroids using the liquid overlay technique. |

Tumor Spheroid Formation Using the I-DOT

| Assessing the effectiveness of the I-DOT, a low-volume noncontact liquid dispensing device, to form spheroids using the liquid overlay technique.
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Using the BIO X to evaluate drug efficacy in aggressive forms of breast and pancreatic cancer in 2D cell cultures vs. 3D bioprinted tumor models. |

Comparing Drug Response in 2D Cultures and 3D Bioprinted Tumoroids

| Using the BIO X to evaluate drug efficacy in aggressive forms of breast and pancreatic cancer in 2D cell cultures vs. 3D bioprinted tumor models.
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3D bioprinting a syngeneic tumor model of murine lung cancer on the BIO X to evaluate an immune checkpoint inhibitor (PD-1) in a 3D T cell cytotoxicity assay. |

3D Bioprinted Tumor Model for Immuno-oncology Applications

| 3D bioprinting a syngeneic tumor model of murine lung cancer on the BIO X to evaluate an immune checkpoint inhibitor (PD-1) in a 3D T cell cytotoxicity assay.
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