3D Bioprinting of a Complex Skin Construct Using the BIO X6 Bioprinter
Whatever the application, from clinical to pharmaceutical to cosmetic, if your research calls for a full-skin equivalent that incorporates multiple cell types and biomaterials, this application note’s full-thickness skin model has you covered. Learn how to leverage premium bioinks and the intuitive automation of the BIO X6’s 6 printheads, photocrosslinking modules, adjustable temperature settings, as well as coaxial attachments to 3D bioprint a multilayered in vitro skin model complete with hypodermis, dermis, epidermis layers, not to mention blood vessels.
Learn about:
- 3D bioprinting a complex hierarchical skin model containing all three layers of hypodermis, dermis and epidermis on the BIO X6.
- Developing a full-skin equivalent for pharmaceutical, cosmetic and toxicity applications.
- Using GelXA FIBRIN and GelMA FIBRIN bioinks to support the differentiation of pre-adipocyte cells after bioprinting and to offer a favorable environment for the development of the dermis layer.
- Leveraging the BIO X6’s coaxial bioprinting attachments to enable the bioprinting of blood vessels.
- Good cell viability and well-defined morphology indications after 14 days using histology staining and live/dead assays.
