BIO X6™

Generation 3 of the most advanced bioprinter enabling high-throughput 3D cell culturing and biofabrication to create the future of health.
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Create multimaterial constructs with a mix of crosslinking modalities thanks to six printheads

6 printheads enabling more complex structures and physiologically relevant models.

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Open biomaterial platform

While we offer an extensive portfolio of biomaterials, we understand the necessity and importance to make the BIO X6 compatible with the widest range of biomaterials available.

Unmatched-resolution
Better Cell Safety
Maintain sterility by leveraging built-in dual HEPA 14 filters and UV-C Germicidal Lights​, as well as through the use of the vertical motorized door
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Intelligent Printheads for flexibility
Six printheads offer significantly increased throughput, cutting down overall print time and improving experiment efficiency. Leverage the use of mechanical, droplet or pneumatic extrusion all in one construct.
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Coaxial & Mixing Printing

Independent dual pressure regulation to seamlessly enable co-axial and mixing printing.

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Multi-material printing

With 6 modular printhead slots, multi-material 3D bioprinting has never been easier.

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Temperature-controlled printbed

The printbed allows temperature control between 4°C – 60°C.

Pushing boundaries with added features

The BIO X has enabled groundbreaking research all over the world. We’re pushing the boundaries even further with the BIO X6.​
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BIO X6
Touchless nozzle autocalibration
4 UV modules
Software on tablet or laptop
6 printheads
Co-axial & Mixing printing
Vertical motorized door
Dual pressure regulation

Highlighted Publications

Immerse yourself in some of the most recent publications that demonstrate the power and versatility of the BIO X6.

Fermentation-Journal-December-2022

Characterization of Biofilm Microbiome Formation Developed on Novel 3D-Printed Zeolite Biocarriers during Aerobic and Anaerobic Digestion Processes

Chioti, Tsioni, Patsatziset al. (2022) Fermentation 8 (12)
The researches used the BIO X6 to print 6 novel zeolite biocarriers, and examined the effectiveness of these 3D-printed biocarriers on methane production Anaerobic Digestion systems, as well as wastewater treatment in Aerobic Digestion, comparing them to commercially available biocarriers.
Advanced Healthcare Materials

Perfusable Biohybrid Designs for Bioprinted Skeletal Muscle Tissue

Filippi, Yasa, Giachino et al. (2023) Advanced Healthcare Materials 12 (8)
Using a sacrificial ink, the researchers were able to achieve microchannels within the printed construct with an impressive 200 µm diameter, supporting both cell survival as well as homogenous alignment in the centimeter-scale construct.
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Rapid meniscus-guided printing of stable semi-solid-state liquid metal microgranular-particle for soft electronics

G-H Lee, Y R Lee, Kim et al. (2022) Nature Communications 13: 2643
In this publication, the researchers made creative use of the printbed heating to evaporate the solvent contained in their ink while printing.

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DNA Studio 4 Compatible

Generation 3 of the BIO X6 harnesses the power of the most advanced bioprinting software available today.

Software

Advanced functionality and versatility.

3D bioprinting with total control of your process.

BIO X6 has you covered however you want your lab set up. The intuitive, onboard software allows you to work from the included tablet or a computer.

Control every aspect of your print from the intuitive and easy-to-use DNA Studio software on your tablet or laptop. Whether it is multilayer printing, layer-by-layer crosslinking, custom material definition or even protocol saving, the BIO X6 software has it all.

Patented Clean Chamber for better cell safety

Built-in UV sterilization and a HEPA filter bring the sterility of the biosafety cabinet to the benchtop.

Four high-powered fans channel air through a HEPA H14 filter to remove 99.995% of unwanted particles and microorganisms as part of the Clean Chamber™ technology, which also includes UV-C germicidal lights, rounded edges and positive air pressure.

Initiate Clean Chamber before beginning your experiment to ensure full sterility around the print area for the duration of the print.

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Open material platform, bioprint with the widest range of materials.

Universal biomaterial compatability

We offer an extensive portfolio of bioinks but understand the importance of material development, which is why we built the BIO X6, part of the BIO X series, to be an open system that is compatible with the widest range of materials available. Start developing your own bioinks with our high-quality bioink development products or explore our ready-to-print and tissue-specific bioinks.

Biomaterials

Excellent temperature control

Bioprint with a wider range of materials and cell types thanks to precise printhead and printbed temperature control.
With a printhead temperature range of 4°C to 250°C and a printbed temperature range between 4°C and 65°C, enjoy precise control of temperatures when working with temperature-sensitive materials like collagen and gelatin. The possibilities are limitless when you are able to work with a wider range of materials and cell types.
Scientist with blue gloves putting a cartridge of bioink into a BIO X printhead

Grow your research with multiple, interchangeable, Intelligent Printheads

Leverage multiple biofabrication modalities on one system with a total of 8 available printheads and toolheads.

With an ever-growing list of Intelligent Printheads, the possibilities are limitless, giving you more freedom to push your research further. Our family of intelligent printheads is always growing. Each printhead system is made to suit different biofabrication application, which helps ensure the best possible result for your 3D bioprint.

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Designed to do even more

The BIO X6’s exceptional features maximize versatility to enhance your success in the following application areas and beyond.​
Application notes
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Spheroid & organoid generation

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3D models for drug discovery

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Organs-on-a-chip

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Food alternatives

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Biosensors

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Organ generation

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Bioassays

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Micropatterning

Technical specifications

Outer dimensions (LxWxH), mm  850x400x500
Weight, kg  47.4 Kg (104.5lb)
Build Volume, mm  128×90×90
Build surface compatibility Multi-well plates, petridishes, glass slides
Resolution XY, μm 1 μm
Layer Resolution, μm  1 μm
Pressure range (internal pump), kPa 1-200
Pressure range (external air supply), kPa 1-700
No. of printhead slots 6
Photocuring sources (built-in), nm 365, 405, 485, 520
Printbed temperature range, °C 4-65
Printhead temperature range, °C 4-250 (printhead specific)
Filter class, chamber air-flow 2xHEPA 14
UV-sterilization UV-C (275nm), 30mW output
Calibration Options Manual and Automatic (Ultrasonic based)
User Interface Tablet or Computer
Desktop Application compatibility Windows
Connectivity USB Storage, Ethernet connection, Wifi
supported file formats, software .gcode, .stl, .amf, .3mf
Power input 100-240V, 50-60Hz, 600W
Fuse 250VAC F6 3A
Structure Powder-coated, aluminum frame

Ready to create the future of health?

Explore how your lab can leverage the BIO X6 and push the limits for your research even further.
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