CELLINK LAMININK 111
Laminins are proteins composed of three subunits referred to as an α-chain, β-chain and γ-chain. They are a major component of the basal lamina that lines the external surface of cell membranes. Its cross-like structure serves as a foundation for many tissues. Laminins play an important role in cell differentiation, migration, adhesion and are involved in supporting healthy tissue.
CELLINK LAMININK 111 is an enhanced formulation of our CELLINK Bioink that contains laminin 111 – an important protein during early development of the lining of tissues and organs. This bioink is suited for 3D culturing of brain, kidney, liver or intestinal cells. In disease modelling, this bioink is relevant for studying Parkinson’s disease and cancer models. The bioink comprises nanosized fibrils, which makes it semi-translucent and allows cell imaging and analysis.
CELLINK LAMININK 111 contains low levels of endotoxins that allows creation of healthy and diseased tissue models with minimal interference with drugs during drug discovery and development research.
Also available with a GelXA base.
This product contains Nanofibrillated Cellulose, jointly patented by UPM-Kymmene Corporation and CELLINK AB.
Uses
- Use as a throughput 3D model (deposited as droplets) with the BIO X Temperature Controlled or Syringe Printhead.
- As a bioprinted 3D construct as demonstrated in the Liver Tissue Model Kit
Other specialized cell specific formulations available:
$249.00 – $999.00
Description
Available in 3 mL cartridges.
Includes crosslinking agent.
Sterile production and packaging.
Six weeks shelf life.
For research use only. Not for human use.
Product number: IKC201000301 (1 x 3 mL)
Product number: IKC201000303 (3 x 3 mL)
Product number: IKC201000305 (5 x 3 mL)
Specifications
The bioink has the following quality criteria:
| Appearance | White semi-translucent gel |
| Sterility | Sterile |
| Endotoxin level | <5 EU/mL |
| pH | 6.5-7.4 |
| Viscosity | ≥5 kPa∙s at 0.01 s-1, ≤3 Pa∙s at 200 s-1, measured at 25°C |
