CELLINK Bioink
CELLINK Bioink is the first universal bioink designed to print human tissue models with any commercially available or in-house developed 3D-bioprinting system. CELLINK Bioink is composed of non-animal derived polysaccharide components only, including alginate and highly hydrated cellulose nanofibrils, jointly patented by UPM-Kymmene Corporation and CELLINK AB. The nanosized fibrils make the bioink semi-translucent and is thus compatible with many advanced imaging techniques. Batch-to-batch consistent and temperature-independent shear thinning properties of the bioink ensure the best 3D bioprinting experience, and morphological similarity of cellulose nanofibrils to collagen provides mammalian cells with a milieu that resembles their fibrillar natural matrix. Altogether, this enables you to bioprint complex, cell-laden tissue constructs, such as cartilage, bone grafts, liver cancer models. After bioprinting, CELLINK Bioink crosslinks easily with the included ionic crosslinking agent.
Specialized Formulations Based off the CELLINK Bioink
$329.00 – $949.00
Description
Bioink comes in 3 mL cartridges.
Includes crosslinking agent.
Sterile production and packaging.
Six-month shelf life.
For research use only. Not for human use
Product number: IKC200000303 (3×3 mL cartridge)
Product number: IKC200000305 (5×3 mL cartridge)
Product number: IKC200000310 (10×3 mL cartridge)
Specifications
The bioink has the following quality criteria:
| Appearance | White semi-translucent gel |
| Sterility | Sterile |
| Endotoxin level | <5 EU/mL |
| pH | 6.5-7.4 |
| Viscosity | ≥7 kPa∙s at 0.01 s-1, ≤3 Pa∙s at 200 s-1, measured at 25°C |
Publications
Markstedt, A. Mantas, I. Tournier, H. Martinez, D. Hägg and P. Gatenholm. 3D Bioprinting Human Chondrocytes with Nanocellulose-Alginate Bioink for Cartilage Tissue Engineering Applications. Biomacromolecules 2015, 16(5), 1489–1496. http://pubs.acs.org/doi/abs/10.1021/acs.biomac.5b00188
Martínez Ávila H, Schwarz S, Rotter N, Gatenholm P. 3D bioprinting of human chondrocyte-laden nanocellulose hydrogel for patient-specific auricular cartilage regeneration. Bioprinting, 2016.
http://www.sciencedirect.com/science/article/pii/S2405886616300045
Michael Müller, Ece Öztürk, Øystein Arlov, Paul Gatenholm, and Marcy Zenobi-Wong. Alginate Sulfate–Nanocellulose Bioinks for Cartilage Bioprinting Applications. Annals of Biomedical Engineering 2016. http://link.springer.com/article/10.1007%2Fs10439-016-1704-5
