- June 18, 2021
Enabling More Complex Geometries with FRESH Bioprinting
FRESH, or Freeform Reversible Embedding of Suspended Hydrogels, was originally developed as a 3D bioprinting method to address the many limitations faced when using soft biomaterials for tissue engineering applications. FRESH 3D bioprinting is performed by extruding bioinks into a LifeSupport™ bath specifically formulated to prevent hydrogel constructs from collapsing and deforming during the printing process. By incorporating ions, enzymes, pH buffers and more, a wide range of polymer crosslinking chemistries and gelation mechanisms can be supported within LifeSupport™.
FRESH has rapidly become the go-to bioprinting platform of choice for many tissue engineers. FRESH enables bioprinting with any soft gelling biomaterial at higher resolutions with no limitations on geometric complexity. FRESH can be integrated into the standard bioprinting workflow and implemented on an extrusion-based bioprinter like the BIO X™. FRESH drastically transforms bioprinting, allowing researchers to tackle the pressing challenges of complex tissue architecture and function. For example, FRESH bioprinting eliminates the need for tedious tasks of ink-specific print optimization, letting researchers skip to bioprinting truly 3D scaffolds and tissues.
Explore some of the most promising potential research directions:

1. Printing tissue-like complexity

2. Creating vascularized tissues

3. Multimaterial bioprinting
Looking to get started on your printing journey?