Laminins are proteins composed of three subunits referred to as an α-chain, β-chain and γ-chain. They are a major component of the basal lamina that lines the external surface of cell membranes. Its cross-like structure serves as a foundation for many tissues. Laminins play an important role in cell differentiation, migration, adhesion and are involved in supporting healthy tissue.
CELLINK LAMININK 111 is an enhanced formulation of our CELLINK Bioink that contains laminin 111 – an important protein during early development of the lining of tissues and organs. This bioink is suited for 3D culturing of brain, kidney, liver or intestinal cells. In disease modelling, this bioink is relevant for studying Parkinson’s disease and cancer models. The bioink comprises nanosized fibrils, which makes it semi-translucent and allows cell imaging and analysis.
CELLINK LAMININK 111 contains low levels of endotoxins that allows creation of healthy and diseased tissue models with minimal interference with drugs during drug discovery and development research.