CELLINK Bioink

CELLINK Bioink is the first universal bioink designed to print human tissue models with any commercially available or in-house developed 3D-bioprinting system. CELLINK Bioink is composed of non-animal derived polysaccharide components only, including alginate and highly hydrated cellulose nanofibrils, jointly patented by UPM-Kymmene Corporation and CELLINK AB. The nanosized fibrils make the bioink semi-translucent and is thus compatible with many advanced imaging techniques. Batch-to-batch consistent and temperature-independent shear thinning properties of the bioink ensure the best 3D bioprinting experience, and morphological similarity of cellulose nanofibrils to collagen provides mammalian cells with a milieu that resembles their fibrillar natural matrix. Altogether, this enables you to bioprint complex, cell-laden tissue constructs, such as cartilage, bone grafts, liver cancer models. After bioprinting, CELLINK Bioink crosslinks easily with the included ionic crosslinking agent.

Specialized Formulations Based off the CELLINK Bioink

$329.00$949.00

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Description

Bioink comes in 3 mL cartridges.
Includes crosslinking agent.
Sterile production and packaging.
Six-month shelf life.
For research use only. Not for human use

Product number: IKC200000303 (3 x 3 mL)
Product number: IKC200000305 (5 x 3 mL)
Product number: IKC200000310 (10 x 3 mL)

Specifications

The bioink has the following quality criteria:

Appearance White semi-translucent gel
Sterility Sterile
Endotoxin level <5 EU/mL
pH 6.5-7.4
Viscosity ≥7 kPa∙s at 0.01 s-1, ≤3 Pa∙s at 200 s-1, measured at 25°C

 

Markstedt, A. Mantas, I. Tournier, H. Martinez, D. Hägg and P. Gatenholm. 3D Bioprinting Human Chondrocytes with Nanocellulose-Alginate Bioink for Cartilage Tissue Engineering Applications. Biomacromolecules 2015, 16(5), 1489–1496. http://pubs.acs.org/doi/abs/10.1021/acs.biomac.5b00188

Martínez Ávila H, Schwarz S, Rotter N, Gatenholm P. 3D bioprinting of human chondrocyte-laden nanocellulose hydrogel for patient-specific auricular cartilage regeneration. Bioprinting, 2016.
http://www.sciencedirect.com/science/article/pii/S2405886616300045

Michael Müller, Ece Öztürk, Øystein Arlov, Paul Gatenholm, and Marcy Zenobi-Wong. Alginate Sulfate–Nanocellulose Bioinks for Cartilage Bioprinting Applications. Annals of Biomedical Engineering 2016. http://link.springer.com/article/10.1007%2Fs10439-016-1704-5

 

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