CELLINK Bioink
CELLINK Bioink is the first universal bioink designed to print human tissue models with any 3D-bioprinting system, commercially available or developed in-house. CELLINK Bioink is a non-animal derived polysaccharide hydrogel that is ideal for 3D bioprinting and cell culturing. CELLINK Bioink is composed of alginate and highly hydrated cellulose nanofibrils, jointly patented by UPM-Kymmene Corporation and CELLINK AB, with morphological similarity to collagen, providing mammalian cells with a milieu that resembles their natural matrix. Its excellent printability enables you to bioprint complex, cell-laden tissue constructs, such as a human auricle. The unique biocompatibility and printability of CELLINK Bioink offer outstanding results that will take your research to the next level! Use our CELLMIXER to mix CELLINK Bioink with a high concentration of cells and a one-step bioprinting process. After bioprinting, CELLINK Bioink crosslinks easily with the included ionic crosslinking agent.
Specialized Formulations Based off the CELLINK Bioink
$297.00 – $841.00
Description
Bioink comes in 3 mL cartridges.
Includes crosslinking agent.
Sterile production and packaging.
Six-month shelf life.
For research use only. Not for human use
Product number: IK1020000303 (3 x 3 mL)
Product number: IK1020000305 (5 x 3 mL)
Product number: IK1020000310 (10 x 3 mL)
Specifications
The bioink has the following quality criteria:
| Appearance |
Opaque gel |
| Sterility | Sterile |
| Endotoxin Level | <40 EU/mL |
| Cell Viability | ≥80% viable mesenchymal stem cells for 7 days |
| pH |
6.5-7.4 |
| Viscosity | 3-20 000 Pa·s |
Publications
Markstedt, A. Mantas, I. Tournier, H. Martinez, D. Hägg and P. Gatenholm. 3D Bioprinting Human Chondrocytes with Nanocellulose-Alginate Bioink for Cartilage Tissue Engineering Applications. Biomacromolecules 2015, 16(5), 1489–1496. http://pubs.acs.org/doi/abs/10.1021/acs.biomac.5b00188
Martínez Ávila H, Schwarz S, Rotter N, Gatenholm P. 3D bioprinting of human chondrocyte-laden nanocellulose hydrogel for patient-specific auricular cartilage regeneration. Bioprinting, 2016.
http://www.sciencedirect.com/science/article/pii/S2405886616300045
Michael Müller, Ece Öztürk, Øystein Arlov, Paul Gatenholm, and Marcy Zenobi-Wong. Alginate Sulfate–Nanocellulose Bioinks for Cartilage Bioprinting Applications. Annals of Biomedical Engineering 2016. http://link.springer.com/article/10.1007%2Fs10439-016-1704-5
