3D Bioprinting of a Complex Skin Construct Using the BIO X6 Bioprinter
For all applications, from clinical to pharmaceutical to cosmetic. If your research calls for 3D bioprinting a full-skin model that incorporates multiple cell types and biomaterials, this application note has you covered. Learn to leverage premium bioinks and the intuitive automation of the BIO X6 3D bioprinter. Plus, its 6 printheads, photocrosslinking modules, adjustable temperature settings, and coaxial attachments enable 3D bioprinting complex skin construct in vitro. The multilayered 3D model is complete with hypodermis, dermis, epidermis layers, not to mention blood vessels.
Learn about:
- 3D bioprinting a complex hierarchical skin model containing all three layers of hypodermis, dermis and epidermis on the BIO X6.
- Developing a full-skin equivalent for pharmaceutical, cosmetic and toxicity applications.
- Using GelXA FIBRIN and GelMA FIBRIN bioinks to support the differentiation of pre-adipocyte cells after bioprinting and to offer a favorable environment for the development of the dermis layer.
- Leveraging the BIO X6’s coaxial bioprinting attachments to enable the bioprinting of blood vessels.
- Good cell viability and well-defined morphology indications after 14 days using histology staining and live/dead assays.
