Description
We offer PhotoHA®, a methacrylated hyaluronic acid (HAMA) for photocrosslinkable hydrogels. These hydrogels provide native-like 3D HA gels with the unique attributes to be prepared at various concentrations and photocrosslinked to provide various gel stiffness.
Hyaluronic acid is the most abundant glycosaminoglycan in the body being an important component of several tissues throughout the body. While it is abundant in extracellular matrices, hyaluronic acid also contributes to tissue hydrodynamics, movement and proliferation of cells, and participates in a number of cell surface receptor interactions.
For the majority of cell types, it is recommended to add additional ECM proteins to the hyaluronic acid hydrogels. The proteins provide important cell binding sites.
Kit 1 – PhotoHA®
#5212-100MG
Item | Catalog Number | Package Size | Storage Temperature |
Methacrylated Hyaluronic Acid | #5212 | 100 mg | -20°C |
Kit 2 – PhotoHA®Stiff – IRG
#5220-1KIT
Item | Catalog Number | Package Size | Storage Temperature |
Methacrylated Hyaluronic Acid | #5212 | 100 mg | -20°C |
Irgacure Photoinitiator | #5200 | 100 mg | 2-10°C |
The product ships on frozen gel packs. Upon receipt, store the PhotoHA® at -20°C. Store the Irgacure at 2 to 10°C. The product and components are stable for a minimum of 1 year at receipt in powder form.
Once solubilized, the PhotoHA® can be stored at 2-10°C for 1 month. The photoinitiator can be stored for no more than 2 weeks once solubilized.
Kit 3 – PhotoHA® Stiff – LAP
#5274-1KIT
Item | Catalog Number | Package Size | Storage Temperature |
Methacrylated Hyaluronic Acid | #5212 | 100 mg | -20°C |
LAP Photoinitiator | #5269 | 100 mg | 2-8°C |
The product ships on frozen gel packs. Upon receipt, store the PhotoHA® at -20°C. Store the LAP at 2 to 10°C. The product and components are stable for a minimum of 1 year at receipt in powder form.
Once solubilized, the PhotoHA® can be stored at 2-10°C for 1 month. The photoinitiator can be stored for no more than 2 weeks once solubilized.
Kit 4 – PhotoHA® Stiff – RUT
#5275-1KIT
Item | Catalog Number | Package Size | Storage Temperature |
Methacrylated Hyaluronic Acid | #5212 | 100 mg | -20°C |
Ruthenium Photoinitiator | #5246 | 100 mg | Room Temperature |
Sodium Persulfate Photoinitiator | #5247 | 500 mg | Room Temperature |
The product ships on frozen gel packs. Upon receipt, store the PhotoHA® at -20°C. Store the Ruthenium and Sodium Persulfate at room temperature. The product and components are stable for a minimum of 1 year at receipt in powder form.
Once solubilized, the PhotoHA® can be stored at 2-10°C for 1 month. The photoinitiator can be stored for no more than 2 weeks once solubilized.
Storage
The product ships on frozen gel packs. Upon receipt, store the PhotoHA® at -20°C. Store the Irgacure at 2 to 10°C. The product and components are stable for a minimum of 1 year at receipt in powder form.
Once solubilized, the PhotoHA® can be stored at 2-10°C for 1 month. The photoinitiator can be stored for no more than 2 weeks once solubilized.
Specifications
Parameter, Testing, and Method | Methacrylated Hyaluronic Acid #5212 |
Sterilization Method | Filtration |
Sterility – USP modified | No growth |
Form | Lyophilized Powder |
Package Size | 100 mg |
Storage Temperature | -20°C |
Shelf Life | Minimum of 6 months from date of receipt |
Shelf Life After Reconstitution | 1 Month |
Degree of Methacrylation | 45-65% |
Molecular Weight | 100-150 kDa |
NMR Analysis | Characteristic |
Hydrogel Young’s Modulus E (Pa) | Characteristic |
Disclaimer
This product is for R&D use only and is not intended for human or other uses. Please consult the Material Safety Data Sheet for information regarding hazards and safe handling practices.