About the webinar
Atherosclerosis develops through a complex interplay between vascular anatomy, blood flow dynamics, and endothelial cell behavior. Yet most in vitro vascular models fail to capture these elements together. Traditional systems often simplify vessel geometry or overlook physiologic shear stress patterns, limiting our ability to study how patient specific anatomy influences disease onset.
In this webinar, Dr. Jorge A. Amaya Catano will present a breakthrough patient‑specific carotid artery model bioprinted on the LUMEN X DLP bioprinter. Generated from MRI data and validated through CFD and PIV, this miniaturized GelMA construct recreates physiologic shear stresses, region‑specific endothelial alignment, and inflammation patterns associated with early atherogenesis.
Join us to learn about:
- Why patient‑specific vascular geometry is crucial for understanding disturbed flow and endothelial dysfunction
- How DLP bioprinting enables anatomically accurate, cell‑laden vessels with smooth muscle and endothelial co‑culture
- Key biological findings, including shear‑dependent endothelial alignment and increased monocyte adhesion in disturbed‑flow regions
- How this platform advances mechanobiology research, personalized CVD risk assessment, and preclinical therapeutic testing
Information
- Dr. Jorge A. Amaya Catano
- 14 Apr. Tuesday
- 9 a.m. CEST | 5 p.m. AEST | 12:30 p.m. IST
