Dr. Gentile will present his studies on how to better engineer the human heart microenvironment using patient-derived stem cells. Cardiac cells differentiated from iPSCs are co-cultured in personalised bioinks as vascularized cardiac spheroids (or “mini-hearts”). This allows the 3D bioprinting of heart tissues in biocompatible hydrogels with optimal cardiac cell viability and function.
– The typical features of the human heart microenvironment and how to better engineer it in vitro
– The generation of vascularized cardiac spheroids as bioinks
– 3D bioprinting of cardiac tissues at UTS in Sydney, Australia