Unmatched capabilities

No other technology can match the speed and resolution of the Holograph X.

Holograph X leverages high-resolution holographic stereolithography to bioprint extremely small structures.

The proprietary multiphoton laser system prints biocompatible materials with up to 150,000 points of light per second to produce a user-generated structure. Users can rapidly print high-resolution structures that replicate human capillaries and ultra-fine extracellular matrices. The printing process is nontoxic and can be performed in the presence of cells.

• We use a high-energy laser to print a true-to-form holographic projection of a researcher-designed or developed 3D CAD file.
• The laser light projection of the 3D image is transmitted into a liquid biopolymer and crosslinked in milliseconds. After printing, the structures can be washed with PBS or water and used immediately.
• Printed structures have a shelf-life of up to six months at 4° C. The biopolymer is transplantable and compatible with extracellular matrix deposition.
• Structures can be seeded with numerous cell types and grown under standard tissue culture conditions.

The technology

• High resolution holographic stereolithography, which enables bioprinting of extremely small structures.
• The proprietary multiphoton laser system prints in biocompatible materials with up to 150,000 points of light/sec in a 3D pattern replicating a user generated structure.
• This allows for extremely rapid 3D printing of high resolution structures that match human capillaries and the finest extracellular matrices.
• The printing process is non-toxic and can be performed in the presence of cells.
• No other technology can match the speed and resolution of the Holograph X.

Benefiting work across your lab

Print any vascular structure you can dream of.

• Researchers can recreate any structure that matches a tissue they want to study.
• Bioinks maybe tuned to print with cells present for immediate local cell layering.
• Bioinks are tuneable such that they may promote or delay biodegradation post transplantation.
• Reliably create and recreate specific tissue architectures to study cell and tissue development.

Wide range of possible structures

• Any user-generated CAD file may be printed.
• Software converts your tissue design into a biocompatible structure that is compatible with cell seeding, long-term cell culture, and animal transplantation.

Micro-devices

• Biocompatible devices such as stents, patches, and drug delivery systems.

Enabling tomorrow's applications

Minature organ replicas

• Mini-organs to mimic cell environments allowing for immune responses etc.
• Build your own complex organs on a chip – interfaces between microfluidics tubes as fine as 10 micrometers.

Single-cell printing

• Single cell encapsulation’ point and encapsulate’ rare cells to separate out later.

Extracellular matrix

• Build tissue structures based on real tissue architecture. These structures can also be transplanted into animals once seeded with cells, allowing the study of human organoids.
• Complex vascular systems that can be seeded with cells and used to develop 3D tissues.

State-of-the-art with infinite flexibility

• This is true optical based printing, that can create structures that other 3D printers can not – the multiphoton process allows printing within already printed structures.
• For example printing inside of already completed structures for local microencapsulation or development of unique surface archtectures is possible.
• Comes with Prellis/CELLINK Software that processes any CAD (.stl) file into a 3D printing hologram –  including real tissue structures from scans of your own.