Automated 3D Cell Culture. Simplified.
As industry leaders in bioprinting, and thanks to our valuable customers, our knowledge of 3D biology research remains unrivaled. This in-depth understanding of 3D biology and our customers’ needs has enabled the development of biodispensing. Through a lens of bio convergence, we have harmonized the best practices within bioprinting with the higher throughput, automation-capable technology present within the liquid handling field. Now we’re introducing the world’s first ever biodispenser – and a new modality to the world of biofabrication. A hassle- and engineering-free method to develop reproducible 3D models which are compatible with existing analysis workflows.
Welcome to the era of biodispensing.
Effortless hydrogel extrusion
Each of the three cartridge stations in the BIO CELLX offer precise temperature control, ranging from 0°C to 60°C, allowing for hassle-free printing of ECM Hydrogels
High throughput like never before
Rapidly plate up to 384-well plates with controlled dispensing
Using positive displacement technology, and features like onboard cell mixing, the BIO CELLX provides unprecedented reproducibility across wells and constructs
The BIO CELLX enables our customers a cost-effective and time-efficient workflow, with high reproducibility at a high throughput. The easy-to-use biodispensing system allows you the time and energy to focus on your research.
See the technology that powers high-throughput 3D Cell Culture
Delve inside the BIO CELLX
Precise & reproducible
The BIO CELLX is a high-precision positive displacement extrusion system. This technology provides reproducible results every single time – regardless of the dispensed material.
CELLINK’s fully enclosed, proprietary Clean Chamber technology, combined with a patent pending de-lidding solution, ensures the sterility of the entire workflow when working on a benchtop in a laboratory environment.
Flexible, validated geometries
Developed by scientists for scientists, pre-validated protocols ensure consistent and reproducible 3D model generation, guiding users through every step of the workflow, from material selection to dispensing to downstream analysis methods.
To achieve an industry-leading positional accuracy, a sensor suite measures the position of each of the dispensing orifices in relation to the position of the vessel. An algorithm compensates any inaccuracies to ensure the precise position of the dispensed model.
Nozzle priming, now with AI
For the first time ever, ensure flawless dispensing courtesy of artificial intelligence-powered nozzle priming, with onboard bubble detection for consistent cell-laden constructs.
No modeling required
Thanks to the variety of 3D models built into BIO CELLX Studio there’s no longer a need to spend time modeling in CAD software.
FEATURE HIGHLIGHT: Proprietary Cartridge
Effortless biomaterial preparation. Every time.
With a novel patent pending dispensing mechanism onboard, the BIO CELLX brings a new degree of ease to creating physiologically relevant 3D models, with the ideal matrix environment, and biomechanical cues for your downstream assays.
Maximize workflow efficiency
Thanks to the automatic mixing of bioinks, reagents and cell suspension, the BIO CELLX significantly reduces the preparation time in your 3D cell culture process.
Automated bioink preparation reduces the variation in mechanical properties, cell viability, pH and air content of samples, enabling consistent results every single time.
Homogenous cell density
With gentle mixing built into the patent pending BIO CELLX cartridges, cell density remains evenly distributed throughout the dispensing process, ensuring reproducible 3D models across wells.
3D geometries to accelerate your discoveries
Droplet is recommended for
Droplet-in-Droplet is recommended for
Triplet Droplet-in-Droplet is recommended for
Line is recommended for
Line-by-line is recommended for
Triple Line-by-line is recommended for
Grid is recommended for
Hydrogel-covered droplet array is recommended for
Areas of Impact
BIO CELLX Studio
Maximize walk-away capabilities through the power of automation. A brand-new intuitive version of DNA Studio guides users through the entire biodispensing process, from setting up the system to selecting one of the pre-set and pre-validated protocols.
No training required.
Enhanced flexibility when required
Custom bioink support
Optimize the dispensing parameters to work with hydrogels that you already know.
Optimize mixing parameters
Adjust mixing parameters to achieve higher cell viability or better homogeneity of the solution.
3D bioprint from STL-files for full freedom of design
Flexible material choice
Dispense up to 3 biomaterials and assign them per well or construct
Interested? Contact us.
Every customer is our partner. Through available and excellent support, our bioprinting application specialists will help you achieve great results.