2300+ Publications
1500+ Labs
Generate Advanced Organoid & Spheroid 3D Cell Models
Explore scalable, reproducible methods for generating organoids and spheroids that are ready for downstream workflows.
Understanding Organoids & Spheroids
Organoids and spheroids are essential 3D cell culture models used to replicate in vivo environments for research, drug discovery, and disease modeling.
SPHEROIDS
- Simple 3D aggregates, commonly just one cell type
- Simpler structure
- Widely used in cancer and drug screening
ORGANOIDS
- Complex, organized multi-cellular aggregates
- Self-organizing structures
- Mimics organ function and architecture
Challenges in 3D Cell Model Development
Despite their advantages, generating consistent and scalable 3D models using traditional methods has remained a challenge.
Limited reproducibility across experiments
Low-throughput for large studies
Manual variability in spheroid formation
Inconsistent microenvironments
Difficulty controlling size and structure
A More Controlled Approach to 3D Cell Culture
3D bioprinting technologies enable precise, reproducible generation of organoids and spheroids, by controlling cell placement, structure, and microenvironment.
CELLINK’s bioprinting platforms and bioinks support standardized workflows for advanced 3D cell models.
- High reproducibility across experiments
- Scalable for higher throughput studies
- Controlled size and geometry
- Near-universal compatibility with ECMs and cell types
Applications in Organoid & Spheroid Research
Drug Screening & Toxicology
Improve predictive drug screening accuracy with physiologically relevant 3D models.
Cancer Research
Generate tumor spheroids (tumoroids) for studying drug response and resistance.
Tissue Engineering
Develop complex structures for regenerative medicine research applications.
Personalized Medicine
Create patient-specific spheroid and organoid models for tailored therapeutic studies.
Trusted by Researchers Worldwide
Used in 2300+ peer-reviewed publications
Adapted by leading academic, industry and pharma labs
Proven across a wide range of application
Having CELLINK as a partner has been very valuable for our research. We received specific answers, and very well-defined and tested materials, ensuring reliable results.
– Prof. Ferdinand Xiankeng Choong
Karolinska Institutet
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TECHNOTE
Automated dispensing and assay of organoids in Matrigel® domes
Download this free workflow guide showcasing how to use the CELLINK BIO ONE and Sartorius Incucyte® Live‑Cell Analysis System for standardized, scalable organoid assays in multi-well plates.
- Method for automated organoid generation in 96 wells
- Combining research-proven biomaterials and tools
- Demonstrated suitability for quantitative pharmacology
Explore CELLINK Solutions
For researchers looking to get started with or advancing their spheroids and organoid workflows, CELLINK offers a range of 3D bioprinters and bioinks.
3D Bioprinters
Precision and flexibility across budget ranges for advanced 3D cell culture.
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Biomaterials
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