Poster Presentation Hours | 18:00 – 19:30 | Poster titles and authors
Drinks and finger food will be provided.
Cecilia Edebo, CELLINK CEO
Our CEO, Cecilia Edebo, will be welcoming you to our CELLINK Partnership Conference 2023.
New materials and manufacturing techniques are emerging with potential to address the challenges associated with the manufacture of pharmaceutical systems that will teach new tricks to old drugs. 3D printing / bioprinting is a technique that can used for the manufacturing of dosage forms and medical implants, and offers a new paradigm for the direct manufacture of personalized dosage forms. The introduction of the fourth dimension has led to an increase in the degree of complexity and customization possibilities of such personalized medical implants. However, 4D printing is still in the early stages, thus research is needed to prove its feasibility in healthcare applications. This talk will provide an overview of current approaches from our research Lab, towards the manufacturing of drug delivery systems and medical devices.
In 2022, the groundbreaking milestone of implanting 3D-bioprinted human tissue in patients was achieved, marking a significant shift in focus from “can we” to “when can we” translate bioengineered tissues and organs into clinical settings. However, substantial challenges remain in the path towards achieving widespread clinical translation.
Join us for this insightful discussion as experts discuss the challenges, considerations, regulations and trends in 3D bioprinting for biomedical applications allowing us to move one step closer to preclinical and clinical translations.
This is the session to advance your g-code script skills. The session will touch on non-planar g-code, what it is and how to implement it in your script. We will also dive into how to write script for very specific movements, tool head specific commands and how to use pp g-code as a tool to fabricate more advanced print patterns.
Level: Advanced
Join us for an inspiring session of Bioprinting Ignited, celebrating achievements and breakthroughs of rising pioneers in the field of bioprinting. This session features the following presentations:
Generation of a Perfusable 3D Lung Cancer Model by Digital Light Processing
Yikun Mei, Technische Universität Berlin
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A comparative study on the suitability of bioinks for 3D bioprinted head and neck tumour model
Alexya Azhakesan, Medical Faculty of Mannheim University of Heidelberg
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3D Bioprinted Vascularized Skin-on-a-Chip Model for Drug Testing and Wound Healing Studies
Federico Maggiotto, University of Padua
This is the workshop session to deepen your light-based bioprinting skills. Learn how to design models for your Lumen X or BIONOVA X bioprinter and how to adapt the light parameters for optimal print quality. We will dive into the questions of how material composition, light intensity, and temperature, among other factors, affect your print and which tools can be used to enable printing of more challenging structures.
Level: Introductory
In this talk, Albane Imbert will provide an overview of the Making Lab Science technology platform work at the Francis Crick Institute, focusing on the development of microphysiological systems and more specifically how to offer reliable tools and methodologies to engineer them. From microfluidics to bioprinting, organoid culture platforms to organ-on-chip, she will discuss opportunities of such tools to be made available on demand in a research institute and the challenges encountered in setting up a new platform for the development of versatile 3D in vitro models.
This is the workshop session to deepen your extrusion based bioprinting skills, learn how to utilise your BIO X and BIO X6 bioprinters full capacity by selecting the right tool head for the right application. The session will focus on how to set up and use the BIO X/X6 bioprinter with the different printheads and how to combine different methods of bioprinting to facilitate a multi-material print.
Level: Introductory
In this talk, Dr. Marco Domingos will provide an overview of Henry Royce Institute’s work in the field of biofabrication for skeletal tissue regeneration. Dr. Domingos will discuss how advanced manufacturing techniques and polymeric inks, mainly those developed in their Lab, can be integrated to support the development of 3D models with tuneable properties and effectively employed in interrogating biological processes associated with tissue morphogenesis. He will highlight some of the major challenges and opportunities in the field of biofabrication and share the vision/mission of the Henry Royce Institute to accelerate the commercial exploitation of bioprinting innovations with potential socio-economic impact in key areas of research including human biology, medicine and drug discovery.
Join us for an inspiring session of Bioprinting Ignited, celebrating achievements and breakthroughs of rising pioneers in the field of bioprinting. This session features the following presentations:
Development and optimisation of highly cellular, embedded bioprinting strategies for the 3D bioprinting of functional cartilage grafts
Kyle Storey, Trinity College
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Exploiting 3D bioprinted models to assess drug response in Chronic Lymphocytic Leukemia
Riccardo Pinos, IRCCS San Raffaele Hospital
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Functional assessment of 3D bioprinted liver tissues from human pluripotent stem cells
Mina Ogawa, McEwen Stem Cell Institute
The research of my group focuses on developing a bioink specifically tailored to replicate the elasticity of the bone marrow environment. By combining our expertise in bone marrow matrix composition with silk biomaterials, we have successfully created a silk bioink capable of supporting the physiological function of human hematopoietic stem cells. Our bioink provides a remarkable opportunity for fabricating 3D bioprinted bone marrow tissue models tailored to track platelet production and function ex vivo.
Join us as we delve into the world of biomaterials and unpack what it takes to develop bioinks of the future. A distinguished panel of biomaterials experts will discuss fabrication technologies and design principles to develop biomaterials supporting heterogeneous cell populations in vitro to accurately model both healthy and diseased tissues.
In this talk, I will present our laboratory’s recent research efforts in using digital light processing (DLP) based bioprinting methods to create 3D tissue constructs using a variety of biomaterials and cells. These 3D printed scaffolds are functionalized with precise control of micro-architecture, mechanical (e.g. stiffness), chemical, and biological properties. Such functional scaffolds allow us to investigate microscale cell-microenvironment interactions in response to integrated mechanical and chemical stimuli. From these fundamental studies we have been creating both in vitro and in vivo precision tissues for tissue regeneration, disease modeling, and drug discovery. Examples such as 3D bioprinted liver, heart and cancer models will be discussed. I will also showcase 3D printed biomimetic scaffolds for nerve repair. Throughout the presentation, I will discuss engineer’s perspectives in terms of design innovation, biomaterials, mechanics, and scalable biomanufacturing.
The liver is both a major drug metabolizing organ and a disease target organ and although several liver in vitro models are available, non-hitherto include all liver cell types and form a vascularized structure. These features are needed to thoroughly evaluate the potential drug effect in liver disease since drug targets not necessarily are expressed in hepatocytes, the most abundant liver cell type. Here we aim to develop a bioprinted liver model that includes the major liver cell types and with a functional bile vasculature and transport. Such a model has potential to improve drug discovery with respect to human translatability and reduce time, cost, and need for animal experiments (3R) when evaluating drug metabolism, toxicity and drug effect for new drug candidates.
There are multiple ways of analysing 3D bioprinted samples, one powerful tool is to extract the cells from the bioprinted sample to thoroughly investigate the cellular expressions. To study the transcriptome, genome and proteome at the single cell level have great impact in revealing cellular functions, discovering relationships across -OMES as well as recording dynamic biological events. Learn together with CELLENION’s research team how the novel and innovative CellenONE technology can be integrated into your bioprinting workflow for high accuracy single cell isolation, precise picolitre dispensing and streamlined transcriptomic and proteomic workflows with minimised manual handling steps, miniaturised sample volumes and optimised protocols.
In short, this session will teach you everything there is to know about how to integrate an optimized omics analysis workflow into your bioprinting workflow.
Level: Introductory
Join world-class experts who are actively developing, validating and promoting non-animal models to define a new gold standard in research, and drive a paradigm shift in safety and efficacy testing. Gain insights into the latest advancements, navigate the challenges, and discover success stories in implementing these innovative models.
Join us for an inspiring session of Bioprinting Ignited, celebrating achievements and breakthroughs of rising pioneers in the field of bioprinting. This session features the following presentations:
Developing dextran-based bioinks for visible lightaided 3D bioprinted cartilage tissue mimics
Sophia Read, University of Manchester
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Bioprinting of nerve guide tubes using a DLP technology
Carlos Paula, Universidade de Coimbra
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Instantly Interfacing Microfluidics with Bioprinted Tissues Using ‘Quick and Dirty’ Multi-Material DLP
Shachar Sofer, Ariel University
There are multiple ways of creating microfluidic and organ-on-a-chip devices, enabling the setup of complex, more complete 3D cell culture workflows. In this workshop we will explore how the precision of light-based bioprinting combined with the flexibility of extrusion-based bioprinting can allow for creation of highly complex, tunable microfluidic and organ-on-a-chip devices. Learn which techniques and tools there are to fabricate your specific designs, and how these can be fabricated in different biomaterial compositions.
Level: Advanced
Do you find it hard to make the 3D bioprinter do exactly what you want it to? The modelling option you are looking for might not be able to be selected, you would like to switch printhead in the middle of a layer or you need the bioprinter to follow a specific geometric pattern. All these targeted edits or specific pathways are possible to create, you just need to open the g-code script. This session will teach you how to read, understand and edit any g-code and give you more freedom in your model creation.
Level: Introductory
The agenda is subject to change.
Join keynote presentations by leading experts in the life science industry. Speakers will showcase real-world examples, providing valuable insights into the challenges, solutions and breakthroughs achieved.
Don’t miss engaging panel discussions featuring esteemed scientists from diverse fields.
Join us as experts share their valuable insights on a range of topics from advanced biomaterials, tissue engineering to clinical translations. These dynamic discussions will provide a multifaceted perspective on the most relevant challenges, allowing attendees to discover new perspectives and engage with Key Opinion Leaders.
Join us for an inspiring session of Bioprinting Ignited, celebrating achievements and breakthroughs of rising pioneers in the field of bioprinting. This session features selected presentations which will showcase the potential of bioprinting in domains such as regenerative medicine, tissue engineering, drug discovery and more. There will be a dedicated time for interactive Q&A, where attendees can engage directly with the speakers and gain deeper insights into their research.
Submit your abstract here to be considered!
Maximize your conference experience with our workshop sessions. Led by CELLINK’s experts, these hands-on workshops provide a unique opportunity to delve deeper into the technical aspects of bioprinting and acquire practical knowledge. Engage in interactive exercises, demonstrations, and collaborative discussions with fellow participants. Select from a wide range of workshops, whether you are a beginner seeking to start your bioprinting journey or an experienced researcher aiming to refine your skills there is a workshop session for you.
To ensure an immersive hands-on experience, the number of participants is limited, so register now!
This is the workshop session to deepen your extrusion based bioprinting skills, learn how to utilise your BIO X and BIO X6 bioprinters full capacity by selecting the right tool head for the right application. The session will focus on how to set up and use the BIO X/X6 bioprinter with the different printheads and how to combine different methods of bioprinting to facilitate a multi-material print.
Level: Introductory
Do you find it hard to make the 3D bioprinter do exactly what you want it to? The modelling option you are looking for might not be able to be selected, you would like to switch printhead in the middle of a layer or you need the bioprinter to follow a specific geometric pattern. All these targeted edits or specific pathways are possible to create, you just need to open the g-code script. This session will teach you how to read, understand and edit any g-code and give you more freedom in your model creation.
Level: Introductory
Please ensure you bring a computer equipped with DNA Studio 4 or any other g-code editor tool.
This is the session to advance your g-code script skills. The session will touch on non-planar g-code, what it is and how to implement it in your script. We will also dive into how to write script for very specific movements, tool head specific commands and how to use pp g-code as a tool to fabricate more advanced print patterns.
Level: Advanced
Please ensure you bring a computer equipped with DNA Studio 4 or any other g-code editor tool.
This is the workshop session to deepen your light-based bioprinting skills. Learn how to design models for your Lumen X or BIONOVA X bioprinter and how to adapt the light parameters for optimal print quality. We will dive into the questions of how material composition, light intensity, and temperature, among other factors, affect your print and which tools can be used to enable printing of more challenging structures.
Level: Introductory
There are multiple ways of creating microfluidic and organ-on-a-chip devices, enabling the setup of complex, more complete 3D cell culture workflows. In this workshop we will explore how the precision of light-based bioprinting combined with the flexibility of extrusion-based bioprinting can allow for creation of highly complex, tunable microfluidic and organ-on-a-chip devices. Learn which techniques and tools there are to fabricate your specific designs, and how these can be fabricated in different biomaterial compositions.
Level: Advanced
There are multiple ways of analysing 3D bioprinted samples, one powerful tool is to extract the cells from the bioprinted sample to thoroughly investigate the cellular expressions. To study the transcriptome, genome and proteome at the single cell level have great impact in revealing cellular functions, discovering relationships across -OMES as well as recording dynamic biological events. Learn together with CELLENION’s research team how the novel and innovative CellenONE technology can be integrated into your bioprinting workflow for high accuracy single cell isolation, precise picolitre dispensing and streamlined transcriptomic and proteomic workflows with minimised manual handling steps, miniaturised sample volumes and optimised protocols.
In short, this session will teach you everything there is to know about how to integrate an optimized omics analysis workflow into your bioprinting workflow.
Level: Introductory
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BIOGRAPHY
Prof Lamprou (Ph.D., MBA) is the Chair of Biofabrication and Advanced Manufacturing at Queen’s University Belfast, the Chair at UKICRS and the Chair of the APS Emerging Technologies Focus Group. Is the author of 150+ peer-reviewed publications, has 350+ conference abstracts, has given 150+ Invited Talks across the world, and has secure Funding more than £3M. Has been recognized as world leader in 3D Printing with PubMed-based algorithms placed him in the top 0.088% of scholars in the world. Has also been named in the Stanford University’s list 2021 & 2022 of World’s Top 2% Scientists. For more info, click here.
BIOGRAPHY
CTO and Board member at Ossiform.
Has several years of experience in the development of additive manufacturing processes of medical devices and patient specific implants.
Lead responsible for Ossiform’s Production, R&D and IP.
Core achievements include the setup of Ossiform’s production conforming to ISO 13485 guidelines, with a production of +1000 implants for premarket testing, validation of the Ossiform material for intended human use, development and subsequent granting of Ossiform’s IP worldwide, as well as the adaptation of the company’s material for Point of Care Printing.
Key contributor in Ossiform’s cumulated capital raise of +$10M.
Has a M.Sc. degree in Engineering of Health Technology.
BIOGRAPHY
Peyman Kelk is a university lecturer in anatomy at the Department of Integrative Medical Biology, Umeå University, Sweden. He obtained his dental degree in 2002 and completed his doctoral studies in the field of periodontology in 2009. In 2013, he became a specialist in prosthodontics and currently holds a combined position where he combines clinical work in prosthodontics with lecturing position in anatomy. His research initially focused on host-parasite interactions, but after his dissertation, he shifted his research towards stem cell biology and regenerative medicine, including 3D bioprinting for hard tissue applications. Today, he works in a larger group of researchers with the aim of making regenerative medicine and stem cell biology clinically applicable.
BIOGRAPHY
Prof. Levenberg is the former Dean of the Biomedical Engineering Department at the Technion. She currently serves as the director of the Technion Center for 3D Bioprinting and The Rina & Avner Schneur Center for Diabetes Research. Prof Levenberg has received numerous prizes including the Krill Prize for excellence in scientific research, awarded by the Wolf Foundation, and was named by Scientific American as a “Research Leader” in tissue engineering, for her seminal work on vascularization of engineered tissues. She has also received the Rappaport Prize for Excellence in Biomedical Sciences and a Medal of Distinction from the Peres Center for Peace and Innovation. Prof Levenberg has authored over 150 publications, and presented her work as an invited lecturer in over 150 international conferences including as a keynote or plenary lecturer. She is founder and CSO of three start-up companies in the areas of cultured meat, spinal cord regeneration and nanoliter arrays for rapid antimicrobial susceptibility testing.
Prof Levenberg earned a PhD at the Weizmann Institute of Science, where she focused on cell adhesion dynamics and signaling, and pursued her post-doctoral research in tissue engineering at MIT, in the lab of Professor Robert Langer. Prof Levenberg spent a year as a visiting professor at the Wyss Institute for Biology Inspired Engineering at Harvard University.
BIOGRAPHY
Ishani Malhotra, Chief Executive Officer, and founder of Carcinotech, has ten years of experience in oncology and stem cell research with degrees from the University of Edinburgh and a Certificate of Achievement from Harvard Medical School. She has experience working at Censo Biotechnologies, HCG Oncology hospitals, The Institute of Cytology and Preventative Oncology and Stempeutics, prior to launching Carcinotech. She was listed as a Director of the Year Regional finalist at the Institute of Directors Scotland 2021 awards, has won several awards at national and international platforms. She was recently recognised as one of 35 Rising Stars by Scottish Business Insider under 35, won the AccelerateHer 2022 Awards for Science and MedTech and won the Female Entrepreneur of the Year award at The Scottish SME Business Awards 2022. She has established significant international partnerships to advance Carcinotech’s vision of providing personalised drug testing platforms to help those suffering from cancer.
BIOGRAPHY
Albane is head of the Making Lab, a Science Technology Platform at the Crick, that focuses on combining approaches from engineering and biomedical research to develop innovative systems to investigate biomedical research questions from neuroscience to cell development, stem cell or cancer biology. She is particularly interested in biomaterial and biomanufacturing processes to develop new in vitro platforms with direct applications to fundamental research conducted at the Crick and the wider research community.
BIOGRAPHY
Dr. Marco Domingos is a Senior Lecturer/Associate Professor in the Department of Mechanical, Aerospace, and Civil Engineering at the University of Manchester (UK). He graduated in Mechanical Engineering (2006) from the Polytechnic Institute of Leiria (Portugal) and holds a Ph.D. (2013) cum laude in Mechanical Engineering from the University of Girona (Spain). He was elected fellow of the Higher Education Academy (UK) in 2016 and fellow of the Institution of Mechanical Engineers (FIMechE, UK) in 2017. He holds several visiting positions at prestigious institutions including visiting Professor at the Centre for Rapid and Sustainable Product Development (CDRSP, Portugal) and at The University of Naples, Federico II (Naples, Italy). Since 2021 he is the Technology Platform Lead for Bioprinting at the Henry Royce (https://www.royce.ac.uk/technology-platforms/bioprinting-platform/), the UK national institute for advanced materials and innovation, where his group is focusing on the development of advanced biomaterials and biofabrication technologies for application in regenerative medicine. He has authored or co-authored more than 50 scientific publications, including articles in peer-reviewed international journals, books and book chapters obtaining over 3436 citations (H index: 26).
BIOGRAPHY
Dr. Alessandra Balduini has a broad background in haematology, with specific training and expertise in the research of haematopoietic stem cell biology and clinical aspects of platelet-related disorders. Since 2007 she has led a research group in two different academic institutions: the Department of Molecular Medicine – University of Pavia (Italy) and the Department of Biomedical Engineering – Tufts University, Boston (USA). The goal was to establish a cross-sectional program that integrates biological with bioengineering approaches to the study of haematopoiesis and bone marrow environment. In 2011 she developed the groundwork for modeling human bone marrow by bioengineering a new 3D model made of porous silk that fully recreates the physiology of the living bone marrow niche environment. This system, completely redesigned in 2015 and 2017, is capable of successfully generating functional platelets ex vivo, offering new opportunities for producing blood components for clinical applications. In 2021, Balduini Lab. proved that this superior tissue system also represents a new tool for studying pathologic mechanisms of human platelet production and testing drug efficiency.
BIOGRAPHY
Dr. Chen is a Professor in the Nanoengineering Department at the University of California, San Diego (UCSD). He is also a faculty member of the Institute of Engineering in Medicine at UCSD. Before joiningUCSD, Dr. Chen had been a Professor and a Pearlie D. Henderson Centennial Endowed Faculty Fellow in Engineering in the Mechanical Engineering Department at the University of Texas at Austin. From 2008 to 2010, Dr. Chen served as the Program Director for the Nanomanufacturing Program in the National Science Foundation (NSF), where he directed the frontiers of nanomanufacturing research at NSF and managed 150 active grants and $18 million annual budget of the program. Dr. Chen’s primary research interests include:
BIOGRAPHY
Dr. Kajsa Kanebratt has an MSc in Pharmacy from Uppsala University, Sweden, after which she did her PhD as an industrial PhD student at AstraZeneca in Mölndal in collaboration with Karolinska Institute in Stockholm. The focus of the thesis was predictive models for induction of cytochrome P450 enzymes, including both in vitro and in vivo studies. In 2009 she joined the In Vitro DMPK group at AstraZeneca in Mölndal as a Senior Research Scientist. Since then Dr. Kanebratt has been working on different in vitro models, most recently driving method development and implementation of 3D liver spheroids within AstraZeneca Mölndal.
Presently, Dr. Kanebratt holds a position as Associate Principal Scientist where she, in addition to laboratory work, also support drug projects from early lead generation to life cycle management with metabolism knowledge and advise.
BIOGRAPHY
BIOGRAPHY
Dr. Charu Chandrasekera is the founder and executive director of Canada’s first and only centre dedicated exclusively to alternatives to animal testing—the Canadian Centre for Alternatives to Animal Methods (CCAAM) and its subsidiary, the Canadian Centre for the Validation of Alternative Methods (CaCVAM) located at the University of Windsor. She obtained her Ph.D. in Biochemistry & Molecular Biology from the Faculty of Medicine at the University of Calgary, specializing in cardiovascular research. Dr. Chandrasekera is an experienced scientist, former animal researcher, science policy expert, and an animal lover. Through CCAAM/CaCVAM, Dr. Chandrasekera promotes the replacement of animals in Canadian biomedical research, education, and regulatory testing through 21st century science, innovation, and ethics.
BIOGRAPHY
Sue Kimber is Professor of Stem Cells and Development at the University of Manchester, UK, Director of the MRC/EPSRC Centre for Doctoral Training in Regenerative Medicine and was Co-Director of the North West Embryonic Stem Cell Centre (NWESCC). She has over 30 years of experience in Cell and Developmental Biology and 10 years of experience in regenerative medicine and tissue engineering using human pluripotent stem cells (hPSCs) with >160 publications. Her lab have derived >30 hiPSC lines both from healthy individuals and those with disease conditions caused by mutations affecting the skeleton, kidney, nervous system and vasculature. They have generated and applied different 2D and 3D protocols for hPSC differentiation of these tissues for understanding human development and disease modelling. She has participated in two UKRI UK Regenerative Medicine Platform hubs (‘Stem Cell Niche’ and ‘Safety of Stem Cells’) and has supervised over 50 PhD students, as well as post docs and fellows. Relevant external activities include Co-Chair of 2023 meeting of European chapter of TERMIS; Founder and Co-Chair of Mercia Stem Cell Alliance to promote stem cell biology in the NW and Midland. She has recently collaborated in several tissue engineering projects using bioprinting.