Human CD8+ T Cells

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Peripheral blood CD8+ T cells, also referred to as cytotoxic T cells, are critical components of the adaptive immune response.  CD8 is a transmembrane glycoprotein which serves as a co-receptor for TCR (T Cell Receptor) to recognize antigens on major histocompatibility complex (MHC).  Once bound, CD8+ T cells kill the infected cell by secreting cytotoxic granules, containing granzymes and perforin, resulting in apoptosis of the target cell.

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Description

Benefits

  • Test negative for mycoplasma, bacteria, yeast, and fungi
  • cells from a variety of donors available
  • Certificate of Analysis provided for each lot purchased
  • HLA typing available

Applications

  • Car-T
  • Immunotherapy
  • Immuno-oncology
  • Immunology

Content

  • 1 x cryopreserved ampule containing ≥ 10 million cells