Fibronectin is a widely used broad range natural cell attachment factor. This product has been purified from human plasma where it is found as a dimer and has a size of 440-500 kDa with two similar subunits (220-250 kDa ) linked by two disulfide bonds. Fibronectin’s primary function is related to cell adhesion and attachment to extracellular matrix. Certain domains of Fibronectin have been found to play important roles that involve interactions with collagen, heparin and other cell surface glycosaminoglycans (GAGs).
Fibronectin is ideal for coating of surfaces and is typically used at a concentration of 1-5 ug/cm2 . It is provided in user-friendly packaging for use and storage. Fibronectin is sterile filtered and is supplied as a ready to use solution after thawing and concentration adjustment. This product is shipped separately on dry ice.
|Parameter, Testing, and Method||Fibronectin #5050|
|Purity – SDS PAGE Electrophoresis||>95%|
|Formulation||20 mM Tris-HCL, pH 7.0 containing 0.45 M NaCl and 12% Glycerol|
|Shelf Life||Minimum of 6 months from date of receipt|
|Cell Attachment Assay||Passes|
|Sterility – USP modified||No growth|
|Safety||Source material found negative for infectious agents|
This product is for R&D use only and is not intended for human or other uses. Please consult the Material Safety Data Sheet for information regarding hazards and safe handling practices.