Laminins are proteins composed of three subunits — α-chain, β-chain and γ-chain. They are a major component of the basal lamina lining a cell membrane’s external surface. Its cross-like structure serves as the foundation for many tissues. Laminins play an important role in cell differentiation, migration, adhesion and the support of healthy tissue.

CELLINK LAMININK 121 is an enhanced formulation of our CELLINK Bioink that can be used as the starting point for culture of multiple cell types. Laminin 121 is expressed widely during embryonic and early development stages of organ and tissue lining. This laminin variation is mostly found in placenta, skeletal muscle and kidney tissue. CELLINK LAMININK 121 is particularly suitable as a base material for culturing cell types including skeletal muscle, brain, kidney and liver cells. Also available with a GelXA base.

Uses

• Use as a throughput 3D model (deposited as droplets) with the BIO X Temperature Controlled or Syringe Printhead.
• As a bioprinted 3D construct as demonstrated in the Liver Tissue Model Kit

Other specialized cell specific formulations available:

• CELLINK LAMININK 111
• CELLINK LAMININK 411
• CELLINK LAMININK 521
• CELLINK LAMININK+