Application Notes

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The fact that the majority of microbial organisms remain unexplored holds enormous potential to discover new metabolic pathways that can be applied in biotechnological processes or used to develop new therapeutics. We present a workflow for exploring such microbial dark matter, based on single-cell isolation and genetic characterization.

Sequencing Single-cell Genomes of Uncultivated Bacteria in the Human Oral Microbiome

The fact that the majority of microbial organisms remain unexplored holds enormous potential to discover new metabolic pathways that can be applied in biotechnological processes or used to develop new therapeutics. We present a workflow for exploring such microbial dark matter, based on single-cell isolation and genetic characterization.
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We introduce a miniaturized, highthroughput workflow in which single HEK293FT cells were sorted by the f.sight™ into 384-well PCR plates, then libraries were prepared with the I-DOT.

Miniaturization and Automation of a full-length Single-Cell RNA-seq Workflow (English)

We introduce a miniaturized, highthroughput workflow in which single HEK293FT cells were sorted by the f.sight™ into 384-well PCR plates, then libraries were prepared with the I-DOT.
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Assessing the effectiveness of the I-DOT, a low-volume noncontact liquid dispensing device, to form spheroids using the liquid overlay technique.

Tumor Spheroid Formation Using the I.DOT

Assessing the effectiveness of the I-DOT, a low-volume noncontact liquid dispensing device, to form spheroids using the liquid overlay technique.
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